/nü-sə prä-bləm/
n. This refers to the problem of transferring data between machines with differing byte-order. The string 'UNIX' might look like 'NUXI' on a machine with a different 'byte sex' (e.g., when transferring data from a little-endian to a big-endian, or vice-versa).
See also middle-endian, swab, and bytesexual.